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Arcolane (Ketoconazole)
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Ketoconazole

Arcolane is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus. Arcolane was first approved in an oral formulation for systemic use by the FDA in 1981. At this time it was considered a significant improvement over previous antifungals, miconazole and clotrimazole, due to its broad spectrum and good absorption. However, it was discovered that Arcolane produces frequent gastrointestinal side effects and dose-related hepatitis. These effects combined with waning efficacy led to its eventual replacement by triazole agents, fluconazole, itraconazole, [voraconazole], and posaconazole. Arcolane and its predecessor clotrimazole continue to be used in topical formulations.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Nolvadex, Norfloxacin, Tambac, Cefobid, Reprexain, Lanacine, Aldezol, Ocid, Levunid, Zeloxim, Bisocor, Isoten, Clora, Renadinac, Glinate, Topimax, Cefspan, Levantes, Repaglinida, Vagimid, Sawacillin, Alpentin, Venlift, Busirone, Mecam, Antiox,

Arcolane is used to treat fungal infections when other medications are not available or cannot be tolerated. Arcolane should not be used to treat fungal meningitis (infection of the membranes surrounding the brain and spinal cord caused by a fungus) or fungal nail infections. Arcolane is in a class of antifungals called imidazoles. It works by slowing the growth of fungi that cause infection.

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Angptl4, an adipokine, was upregulated in DM-BMCs compared to non-DM-BMCs. Theoretical study for the treatment of pancreatic cancer using electric pulses. As the immunologic defects become better defined, the cells of the myeloid lineage are emerging as the primary players. The aim of this study was to compare hsCRP levels between normal weight women with PCOS and controls with a normal menstrual cycle and to determine the factors associated with serum hsCRP levels. The aims of these case reports were to clarify the clinical characteristic of the dynamite explosion burn-blast facial injuries and discuss appropriate management of these patients.

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Subsequently, palliative radiation therapy of 50 Gy in 25 fractions was administered and was temporarily effective. Evaluation of expression of polymorphonuclear neutrophil surface receptors in patients with type 1 diabetes

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For both impairments, treatment with more than one psychopharmacological drug is common, although little is known about efficacy and side effects of polypharmacological treatment. The risk of lung and urinary bladder cancers was reported to be increased in individuals who carried high risk genotypes in either cytochrome P450 (CYP)1A1, CYP2E1 or glutathione S-transferase (GST)M1, and the combined genotype of both CYP1A1 and GSTM1 enzymes have an enhanced tendency of risk to lung cancer more significantly.

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The effects of whole-body x-irradiation on peritoneal fluid cells and peripheral blood leukocytes in pollen-sensitized rats. The applications of graphene cover a wide range of possibilities, from next-generation transistors to light-weight, high-strength composite materials. Dogs with LGHL injury can be treated using this novel technique with low complication rates and good outcomes after 6 months.

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Community health nursing ready to meet the challenges of health reform. We carried out a study on 50 fetuses of singleton pregnancies undergoing invasive procedures -- at least three per fetus -- for diagnostic and therapeutical purposes. These results demonstrate that the phenotype of cartilage growth, and the associated balance between proteoglycan content and integrity of the collagen network, is regulated differentially by certain growth factors. Sex differences in visual-spatial ability: the role of performance factors.

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Heart-lung transplantation for cystic fibrosis and subsequent domino heart transplantation. The bases for both toxicity and protection are not clearly understood. Review of the literature showed that there is a control center of voluntary cough in the right inferior frontal gyrus. Mechanisms of action of the intragastric balloon in obesity: effects on hunger and satiety.

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Energy density of nonminimally coupled scalar field cosmologies. We conclude that the clinical significance of an arthroscopically defined partial PCL tear in an ACL-deficient knee is minor, and that isolated ACL reconstruction in this setting appears to be effective treatment. Deoxyhemoglobin-mediated lipid oxidation was studied by comparing the pro-oxidative activity of anodic and cathodic hemoglobins from trout in a washed cod muscle model system.

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Pain and tissue-interface pressures during spine-board immobilization. Failure to improve cardiopulmonary fitness in cardiac rehabilitation. This is a report of two Iranian patients (father and son) with severe level of whole blood lead concentration, developing into unconsciousness.

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Results showed that the predominant cytoskeletal response was massive formation of actin-containing filopodia at the cell surface that could be related with Cdc42 activation and increased vinculin immunocontent. When the distribution of liposomes in healthy and tuberculous mice was compared, a greater accumulation in the liver, spleen and lungs of healthy mice was observed, although the retention time in tuberculous mice was longer. The situation is clear, there needs to be a greater number of donors coming forward from the Asian communities to increase the pool of suitable organs.

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The mesoporous structure of niobium oxide (MNb) is beneficial to the N dopant that is effectively incorporated into the lattice of MNb, resulting in a significantly enhanced visible light response. The quality of health care towards the common cold may be markedly improved in most of the centers studied. MALAT1 promotes cell proliferation in gastric cancer by recruiting SF2/ASF.

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Contribution of breastfeeding to the reported variation in rates of mother-to-child HIV transmission. Circular dichroism has also been applied to quantitate enantiomeric purity in composite samples without any separation of the analytes, and also, to determine equilibrium constants of protonating chiral compounds. The degree to which each of these effects is observed varies considerably between experiments. Interaction between mutations and regulation of gene expression during development of de novo antibiotic resistance. Possible simplified gravidity technique for detecting physiological resistance of Anopheles gambiae to BHC.

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Vocabulary for health information ontology was mapped to the Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT), and a list of about 1,500 terms was proposed. Effect of tetraiodothyrobutyric acid on the metamorphosis of Rana temporaria tadpoles

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Chromosome mapping and organization of the human beta-galactoside alpha 2,6-sialyltransferase gene. Central motor conduction time in the upper limb was prolonged in three patients (five sides) and in the lower limbs in one (both sides), which was consistent with involvement of the cerebral cortex, thalamus, brainstem, and spinal cord. If it is assumed that the same cellular mechanisms are responsible for spindle frequencies in humans then the study of variations in spindle frequency could be used to examine the NREM sleep process in humans. The specificity of the Zif268 findings was assessed by quantifying mRNA levels for other immediate early genes.

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It was the aim of this study to develop an oral capsule delivery system capable of rapidly ejecting the incorporated payload in the small intestine. Health fair screening may be an effective approach for the identification of individuals with undiagnosed IA/RA. The studied areas are distributed from north to south along the western margin, with the northernmost located off shore the Ave and Douro rivers, a central one located off shore the Lis River and a southern one located off shore the Mira River. Sulfatides partition disabled-2 in response to platelet activation.

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Plasma YKL-40 levels are elevated in patients with CHF but show no association with other clinical or paraclinical variables. Relapse, not regimen-related toxicity, was the major cause of treatment failure in 11 children with Down syndrome undergoing haematopoietic stem cell transplantation for acute leukaemia. tularensis to persist using chitin as a sole carbon source is dependent on chitinases, since mutants lacking chiA or chiB are attenuated for chitin colonization and biofilm formation in the absence of exogenous sugar. There is lack of data about the link between FT3 levels and malnutrition and inflammation in hemodialysis patients. Sex education: views and proposals of students and teachers in secondary schools in Asturias, Spain

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Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factor. To this end the OmpF porin trimers from Escherichia coli was reproducibly imaged at a lateral resolution of approximately 0.5 nm and a vertical resolution of approximately 0.1 nm at variable electrolyte concentrations of the buffer solution. Tick-borne encephalitis: from childhood to golden age does increased mobility mean increased risk?

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A quantitative study of the Purkinje cell dendritic branchlets and their relationship to afferent fibres. It is therefore the earliest and most primitive representative of the largest assemblage of fossil and living reptiles, collectively called diapsids. Uveal MALT lymphoma with extensive AL-type amyloid production mimicking uveal melanoma. We analyze the possible clinical differences between bone jaw exposed areas in ONJ (osteonecrosis of the jaws) and ORN (osteoradionecrosis).

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Cell isolation in the presence of latrunculin B, an actin polymerization inhibitor, did not cause the disappearance of AIL cells from cell suspension. A high-efficiency combinatorial approach has been applied to rapidly build the database of composition-dependent elastic modulus and hardness of the Ti-Ta and Ti-Zr-Ta systems. Except for one article addressing issues related to the preventive management of exercise-induced anaphylaxis, all other articles focused on prevalence rates, causative triggers and pathogenetic mechanisms. If patented STD drugs are required drug cost may be minimised by selecting the most appropriate management protocols and by improving procurement.

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In this article, we consider the analysis of longitudinal data on the number and size of premalignant clones, formed by clonal expansion of initiated cells. Femoral condyles, interepicondylar distance, length and thickness of the MPFL were measured.

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Effect of acute and long-term smoking on myocardial blood flow and flow reserve. We study the spatiotemporal pattern of spread in the remotely located and sparsely populated region of North Norway in various models with fixed, seasonal, and random effects. Comparison of surveillance methods applied to a situation of low malaria prevalence at rural sites in The Gambia and Guinea Bissau. Five patients had normal visual fields after treatment, and one patient had residual visual field loss.

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The design, synthesis and testing of desoxy-CBD: further evidence for a region of steric interference at the cannabinoid receptor. Liquid human milk fortifier significantly improves docosahexaenoic and arachidonic acid status in preterm infants. Our results indicate that the average concentration of total PAHs in this region reached a moderate pollution level, which was higher than that in other larger estuaries in Asia. Efficient expression of transgenes in vivo is of critical importance in studying gene function and developing treatments for diseases.

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Effects of electropermeabilization after the administration of anticancer drugs on transitional cell carcinoma. Abnormal embryologic events disrupt the formation of the diaphragm allowing the abdominal viscera to occupy the intrathoracic space. The canine guide generated greater tensions in the region of the first implant, while the bilateral balanced occlusion generated great tensions in the entire metallic framework.

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Controversies about interspinous process devices in the treatment of degenerative lumbar spine diseases: past, present, and future. Preparation of prostaglandin H2: extended purification/analysis scheme. Many emergency nurses and physicians lack adequate knowledge about this phenomenon to make an accurate diagnosis. Factors influencing adaptation and performance at physical exercise in complex congenital heart diseases after surgical repair.

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We discuss these emerging dolaut gel opinioni e criteria for gene prioritization and the potential impact on the field of neuroscience. The putative mechanisms by means of which oestrogens may exert effects on neurotransmitters and peptides are discussed in the article. Determination of 2,4,6-tri-tert-butylphenol and related compounds in foods cDNA clones encoding beta-ketoacyl-acyl carrier protein synthase III from Cuphea wrightii.

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CD30 positive H/R-S cells were isolated with micromanipulator from the frozen sections and analyzed by single-cell PCR. Human immunodeficiency virus type 1 (HIV-1) heterogeneity contributes to the emergence of drug-resistant virus, escape from host defense systems, and/or conversion of the cellular tropism. Conversely, septally located cells received multiwhisker input from both subcortical and cortical sources. Efficacy and safety of intra and periarticular corticosteroids injections in treatment of lupus arthritis. Involvement of C2H2 zinc finger proteins in the regulation of omeprazole otc sam's club bakery epidermal cell fate determination in Arabidopsis.

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Concavocorona, a new genus of the leafhopper subfamily Evacanthinae (Hemiptera: Cicadellidae), with description of a new species. Studies involving measurement of glucocorticoid receptor mRNA and binding sites have revealed that glucocorticoid receptors are subject to autoregulation. Plasma Th1 and Th2 cytokines increased with time in the chronic group and correlated with the degree of pulmonary vascular remodeling. Visual detection method for identifying recombinant bacterial colonies. After budding colectores uricon dosage off the germinal ridge (a compartment of the luminal epithelium), nascent follicles then enter into a linear array of developing follicles within which temporal and stage-specific events can be correlated with spatial distribution.

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