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Coxib (Celecoxib)

A synergistic effect was observed in inhibition of cell growth when the cells were exposed to various concentrations of Coxib combined with curcumin. Despite the lack of improved upper gastrointestinal safety with Coxib and the evidence of cardiovascular risk with rofecoxib, both agents had widespread clinical use for 4-5 years.

Other names for this medication:
Celecoxib, Celebrex, Artilog, Artose, Caditar, Celcox, Celcoxx, Celebra, Celeco, Celemax, Ciox, Colcibra, Coxib, Dilox, Dorex, Dorit, Flaxel, Impedil, Lexfin, Onsenal, Sionara, Solexa, Zycel,

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Coxib is used to relieve pain, tenderness, swelling and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). It is also used to treat juvenile rheumatoid arthritis (a type of arthritis that affects children) in children 2 years of age and older. Coxib is also used to treat painful menstrual periods and to relieve other types of short-term pain including pain caused by injuries, surgery and other medical or dental procedures, or medical conditions that last for a limited time. Coxib is in a class of NSAIDs called COX-2 inhibitors. It works by stopping the body's production of a substance that causes pain and inflammation.

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First, compared with naturally cycling (NC) women in the luteal phase, women on hormonal contraception (HC) would have significantly blunted hypothalamic-pituitary-adrenal reactivity to physical stress. By immunoperoxidase staining, the tumor cells were positive for IgG and kappa chain, but they were negative for lambda chain. Electronic structure of antimony from density-functional calculations and angle-resolved photoemission.

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B7-H1, a member of B7 family, is expressed in tumor cells and has emerged as an important immune modulator capable of suppressing host immunity by inhibiting T cells function. Ultrafast dynamics in Na-doped water clusters and the solvated electron. One important issue is that the patient went to see her family doctor instead of resorting to complementary consultations. It is suggested that a difficulty in modifying responses, especially when followed by negative consequences, as manifested in these simple laboratory tests, may contribute to the inappropriate behaviour shown in daily life by patients with frontal lobe damage. Under the diagnosis of craniopharyngioma, almost all of the tumor was removed, using the transsphenoidal approach.

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We performed a genome-wide mapping, which yielded a locus of 12.4 Mb on chromosome 21q21. This review describes the fundamental concepts of left atrial STE, illustrates its pathophysiological background and discusses its emerging role in systemic arterial hypertension.

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Infestation of urban populations of the Northern white-breasted hedgehog, Erinaceus roumanicus, by Ixodes spp. This may further support the potential effectiveness of NMDA blockade during repeated use of morphine for control of chronic pain. To determine the feasibility and efficacy of a fiberoptic probe containing novel polarization gating spectroscopy technology to identify patients with pancreatic adenocarcinoma (PAC) by the field effect theory. On the potential application of superalkali clusters in designing novel alkalides with large nonlinear optical properties. Antitumor activity of FCE 26644 a new growth-factor complexing molecule.

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Prolonged left ventricular assist device support (18 months) in refractory ventricular fibrillation. Liquid chromatography/mass spectrometry for the identification and quantification of rhamnolipids. Low-power operation of vertically aligned liquid-crystal system via anatase-TiO(2) nanoparticle dispersion. A multicenter prospective study of infections related morbidity and mortality in cirrhosis of liver. Metal oxide nano-wires are crystalline structures with precise chemical composition, surface terminations, and dislocation-defect free.

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Having briefly analyzed the metabolism of ethanol in elderly subjects and the evidence of great resistance of the senile liver to alcohol-induced damage, the Author describes histological, clinical, biohumoral features of fibrosis and the necessary therapeutic measures. Among African-American women with PID, we observed trends between TLR2 variants, BV/intermediate flora, and BV-associated microbes.

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Thus, the University Hospital and University of Lausanne (CHUV) recently improved intern processes of back pain care. The purpose of this project was to evaluate the relationship between self-efficacy and advancing academic aspirations of registered nurses.

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Isothiazolinones are present in multiple products registered for use at workplaces, and may occur in high concentrations. The isolated SlyA protein is a cofactor-free homodimer that recognizes five sites within the promoter region of the slyA gene. Electrically measuring viscoelastic parameters of adherent cell layers under controlled magnetic forces. Dendrimers in Supramolecular Chemistry: From Molecular Recognition to Self-Assembly. The results suggest that the UFOV may be a valuable instrument for assessing driving readiness in TBI survivors.

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One approach not extensively pursued, has been the use of yeast as a model system for functional analysis of different aspects of phospholipase signalling. MRI demonstrated characteristic thinning of corpus callosum, dominant in anterior portion.

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Herein, we present, for the first time, a transduction approach for the direct and rapid (30min) detection of small amphiphilic biomarkers in complex samples (e.g. Mercury-nutrient signatures in seafood and in the blood of avid seafood consumers. In patients with different stages of CKD, the increase in FGF-23 levels, as glomerular filtration rate reduced, outstripped that in the serum levels of phosphorus and intact parathyroid hormone. Epidemiologic effectivness of poludane in preventing influenza and other acute respiratory diseases in troops

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Pleomorphic carcinoma of the lung may display various histopathological changes making it easy to be misdiagnosed as carcinosarcoma. The custom-made artificial semi-knee joint based on computer-aided design can afford satisfactory knee joint function recovery following allograft bone transplantation. This technique is promising as a tool for clinically sampling substances that are freely distributed in the body and as a model for studying inflammation and vascular permeability. The best-fitting model included only fixed effects for moderate or severe problems in each of the 5 EQ-5D dimensions and excluded a constant.

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TEF-1 and CSEF-1 were distinguished by differential migration as GT-IIC complexes, thermal stability, molecular mass, and cross-reactivity with chicken TEF-1 antibodies. The performed abrasion probatoria showed full correspondence with exception of 3 cases.

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Allergic manifestations of the female patient from puberty to menopause. Herein, we aimed to determine the roles and the hierarchical organization of the PAX6-dependent gene regulatory network during the differentiation of the retinal pigmented epithelium (RPE). An evaluation of a mixed-gender sexual assault prevention program. Investigations varied considerably regarding the experimental design. Mice were given an intraperitoneal (i.p.) injection of CDDP-MC 24 h after inoculation with tumor cells.

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3 Cases of panophthalmitis caused by Bacillus pyocyaneus after cataract surgery The enzymatic activity responsible for furfural reduction was considerably higher than for HMF reduction and also in situ furfural conversion was higher than HMF conversion. The vibrational spectra indicate that the main compositions of the Amanitaceae mushrooms are protein and carbohydrate. The increase in Se-GPx activity observed in patients with retinopathy could be linked to the protective effect of zinc on the protein itself.

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Avoiding the use of a main body, ILEs are simultaneously delivered from both femoral arteries, landing parallel into the aortic neck (parallel grafts: PG). Intracranial hemorrhage was the most common concomitant injury across most age groups.

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Anthracycline therapy decreases aortic distensibility in patients with lymphomas. Struggling to survive: the difficult reality of Aboriginal women living with HIV/AIDS.

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Thermochemical nanolithography (TCNL) is a high-resolution lithographic technique and, owing to its fast speed, versatility, and unique ability to fabricate arbitrary, gray-scale nanopatterns, this scanning probe technique is relevant both for fundamental scientific research as well as for nanomanufacturing applications. In vivo evidence for brain-to-blood efflux transport of valproic acid across the blood-brain barrier.

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Microfabrication techniques have been applied to experiments on surface-enhanced Raman scattering, transport in one-dimensional conductors, and macroscopic quantum tunneling. Since ICPD, the decline in unsafe abortion was slower than that in safe abortion, and unsafe-abortion-related mortality continued to be a problem. One eye of 70 consecutive glaucoma patients and 28 age-matched normal subjects was studied.

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Association of anti-Helicobacter pylori neutrophil-activating protein antibody response with anti-aquaporin-4 autoimmunity in Japanese patients with multiple sclerosis and neuromyelitis optica. This hypothesis was investigated by studying the hepcidin response under modulation of iron availability.

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Instantaneous diffusion in spin-echo dynamics: A frequency-domain experimental investigation. Those subjects who completed only 3 weeks had significantly more pathological personality traits than those who continued in the study.

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During the study period there were no false positive or false negative results in our unit using the above criteria. In vitro anti-inflammatory activity of phenolic rich extracts from white and red common beans.

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This paper provides useful information for health care professionals to consider how to enhance IDM of older adults regarding the use of sensor technologies. Based on the current evidence, LRA shares similar safety with RRA for CAG and is superior to RRA in certain respects. Although the distribution of nNOS in the NTS has been well documented, the distribution of eNOS in the NTS has not. By using specific inhibitors to histone modification enzymes, HDAC3 was identified to specifically augment the autoactivation of neuroD in P19 cells.

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Rupture of the Achilles tendon in athletes: do synthetic grass fields play a part? The aim of this paper is to develop a conceptual framework, which can be used to explore the relationship between spirituality and health. The objective is to determine how leave trends vary within the year, and determine whether trends are predictable. Second, we show that Ine is able to control excitability from either neurons or glia cells.

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In these patients, problems may arise with anticoagulation and antiarrhythmic therapy due to the inherent locomotor instability associated with the disease, and the presence of concomitant atrioventricular disease. Max Wertheimer, Habilitation candidate at the Frankfurt Psychological Institute. Adrenocortical reactions following parenteral administration of egg white in the albino rat There is an urgent need to educate dental students about epilepsy. These strands are connected by loops that vary in size and structure and make up the closed and open ends of the pocket.

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The target subjects were people with HIV infection who were treated as outpatients at core hospitals for acquired immune deficiency syndrome (AIDS) treatment in Japan. The Flex-R file was compared with the Lightspeed nickel-titanium file in respect to canal center movement and final canal area after instrumentation.

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The effects of panaxydol on cell proliferation, morphologic changes, glial fibrillary acidic protein (GFAP) expression and cell cycle regulation in rat C6 cells were evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, hematoxylin and eosin (HE) staining, immunocytochemistry, flow cytometric analysis and Western blot respectively. In this condition most subjects focused their attention on the clear sensation of the de-afferented hand region. The base case modeled a cohort of 55-year-old patients with OA for a 12-month period of treatment, followed by treatment from a basket of post-discontinuation oral therapies until death.

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The possibility of penetrating aortic ulcer should be considered in the differential diagnosis of aortic aneurysm. One of the major obstacles in cancer therapy is the ability to target specifically cancer cells.

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An orientation to this improvisational dance as an embodied practice and experience is given. Those patients who had recurrence of disease tended to be more allergic, have higher Lund-Mackay score, and had an increased number of prior sinus surgeries. A predominance of small, more mobile particles is a risk factor for cardiovascular disease. Knowledge of Iranian medical interns regarding cardio-pulmonary resuscitation.

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The atrial natriuretic peptide (ANP) has been suggested to possess immunomodulatory potential because of its property to alter macrophage functions via its guanylate-cylcase- coupled A-receptor (NPR-A), such as inhibiting the expression of inducible nitric oxide synthase or TNF-alpha. Effects of chemical contaminants on growth, age-structure, and reproduction of Mytilus edulis complex from Puget sound, Washington. The women-to-men ratio increased from 1.70 for patients born in the 1930s to 2.67 for patients born in the 1980s. An immersed-boundary method for flow-structure interaction in biological systems with application to phonation. In the younger population with inflammatory arthritis, noncemented TEA has reliable outcomes clinically and radiographically at long-term follow-up.

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Valuable trace evidence is often lost or destroyed because of faulty collection and preservation techniques during surgical management of gunshot wounds. Mixed-forest species establishment in a monodominant forest in central Africa: implications for tropical forest invasibility.

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Prediction of recurrent and residual cervical dysplasia by human papillomavirus detection among patients with abnormal cytology. The statistical analyses were applied using descriptive statistics with the Statistical Package for the Social Sciences version 20.0. The neuroprotective effects and the increases in phospho-Akt and phospho-ERK were abolished by administration of phosphatidylinositol 3-kinase-Akt inhibitor LY-294002 or ERK inhibitor PD-98059. No significant findings were found when comparing the results between high- and low-educated men. The axial movement function was obtained from a three-dimensional reconstruction of a biplanar coronary angiogram.

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Medulloblastoma, a malignant, invasive embryonal tumor of the cerebellum, occurs most often in children. Some suggestions for inclusion in a training programme are given. Flow cytometry pulse width data enables rapid and sensitive estimation of biomass dry weight in the microalgae Chlamydomonas reinhardtii and Chlorella vulgaris.

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In regard to mossy fiber sprouting, a wide variety of experiments involving intracellular or whole-cell recordings during electrical stimulation of the hilus, glutamate microstimulation, and dual recordings from granule cells support the hypothesis that mossy fiber sprouting forms new recurrent excitatory circuits in the dentate gyrus in animal models of TLE. Analysis of the interaction between experimental and applied behavior analysis.

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Maternal heart rate and blood pressure and fetal heart rate were assessed before the test dose and at five minute intervals until the end of surgery. We found that only inhibition of ERK1/2 significantly decreased the activation of MMP13 in response to FGF stimulation, suggesting that activation of FGFR signaling may activate ERK/MAPK, rather than JNK or PI3K pathway to activate MMP13 expression in 8,226 cells.

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Comparison beta-blockers and their relevance to pharmacologic therapy of cardiovascular diseases A drawback may be the technical expertise required, particular in centers dealing with low numbers of complex abdominal trauma. It is with these tools and knowledge that the clinical laboratory can contribute substantially to overall patient care. If this technique is combined with T2WI and DWI, its diagnostic value is enhanced.

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In Western blot analysis of spinal cord extracts, c-Jun/sc45 antibody weakly detected a 39-kD band, corresponding to c-Jun, and more strongly detected two additional bands of 66 and 45 kD which followed developmental changes coincident with naturally occurring or experimentally stimulated apoptotic motoneuron death. Furthermore, the effect of nitrogen deficiency on the nitrogen sources and phosphorus sources utilization rate and the COD removal rate was studied in the experiments. We used a chronic cerebral hypoperfusion model by permanent stenosis of bilateral common carotid artery in mice to study microglial activation and autophagy.

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MDMA-pretreated Dark Agouti rats demonstrated a statistically significant reduction in anxiety-related behaviour, compared to saline-pretreated control rats, in both the elevated plus-maze and open field when the rats were tested on metronidazole gel pretty day 73 (open field) and day 80 (plus maze) after MDMA administration. The patient was immediately treated by a balloon occlusion and complete packing of the cavernous carotid artery using Guglielmi detachable coils (GDCs) and the rest of the tumor was removed after the carotid occlusion.

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The concentrations of 16 polycyclic aromatic hydrocarbons (PAHs) were determined in the soils from industrial, wharf, cropland, milldam and natural wetland sites to characterize their distributions, toxic levels and possible sources in the gabapentin toxicity in renal failure the importance of dose adjustment Pearl River Estuary and identify their relationships with soil organic matter (SOM) and water-stable aggregates (WSAs). The pharmacologic use of plants and herbs (phytotherapy) for the treatment of LUTS associated with BPH has been growing steadily. Routine opt-out HIV screening: more evidence in support of alternative approaches? Subcutaneous panniculitis-like T-cell lymphoma: expression of cytotoxic-granule-associated protein TIA-1 and its relation with Epstein-Barr virus infection Imaging of cellular oxygen and analysis of metabolic responses of mammalian cells.

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To evaluate the effects of oral appliance (OA) treatment upon systemic blood pressure (BP) in mild to combivir side effects liver moderate patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). To compare the skeletal benefits associated with gymnastics between ulna and radius.

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