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Cycloxan (Cyclophosphamide)
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Cyclophosphamide

Cycloxan is a cytotoxic (cytostatic), cell-cycle-nonspecific, antiproliferative agent that is used in such diverse medical problems as neoplasia, tissue transplantation, and inflammatory diseases. It is an inert prodrug for a potent nitrogen mustard alkylating agent. After the metabolic activation of Cycloxan to the potent mustard by liver enzymes, a nonenzymatic generation of chemically reactive molecules occurs. These reactive molecules can form covalent bonds with biologically ubiquitous groups, such as amino, phosphate, hydroxyl, carboxyl, sulfhydryl and imidazole, and as a result, depending on dose, Cycloxan is capable of either interfering with the reproduction of cells or killing cells. This is especially true in the case of rapidly dividing cells.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Cycloxan is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Cycloxan is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin). It belongs to the group of cancer medicines called alkylating agents.

Cycloxan is also used for some kinds of kidney disease.

Cycloxan interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by Cycloxan, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with Cycloxan, you and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule
  • Powder for Solution
  • Tablet

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Determination of the potential for fundamental- and adjoint-representation sources in SU(2) in three dimensions. hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein. To study possible alterations in mucin sulphation and mucin secretion, which could be the cause of decreased mucosal protection in ulcerative colitis. Theoretical models show that varying pulse duration influences residual thermal damage in erbium YAG skin resurfacing.

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Autoradiographs of polyethylene spherulites containing low molecular weight tritiated polyethylene exhibited concentric ring patterns similar to those observed on viewing the polymer film in a polarizing microscope. To get complementary information from plasma samples, we used three different proteomic approaches, namely 2D-DIGE, SELDI-TOF-MS and 2D-LC-MS(E). Purification and characterization of membrane-bound hydrogenase from a thermophilic hydrogen-oxidizing bacterium, Pseudomonas hydrogenothermophila strain TH-1.

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Sudden death in Unverricht-Lundborg patients: is serotonin the key? The human transferrin receptor (TfR) contains three N-linked oligosaccharides and glycosylation is required for the proper folding and function of the molecule.

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The apoptosis-inducing effect of noradrenaline was mimicked by isoproterenol and blocked by propranolol, which indicates that noradrenaline triggers apoptosis via a beta-adrenergic signaling pathway. New atrial fibrillation classification by electrocardiogram will help general practitioners deliver personalized treatment. Use of the oral diuretics, aminometradine and aminoisometradine, in the sodium and water retention of hepatic cirrhosis.

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The relationship between knowledge and clinical performance in novice and experienced critical care nurses. The Low Contact Stress (LCS) Total Knee System (DePuy Orthopaedics Inc, Warsaw, Ind), a mobile-bearing knee arthroplasty design, was introduced in 1977. Study of the comparative action of corn oil and butter in experimental dyslipoidosis in rats This situation places them in a position to influence life-styles. Biobank policy and regulations profoundly vary between different societies.

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INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization. Virus infection and inflammation alter protein N-glycosylation, and we have previously shown that changes in cellular N-glycosylation are involved in regulation of NKG2D ligand surface expression. The delay in diagnosis averaged four years with the most common mistaken diagnosis being cervical disc disease. Overall, our results demonstrate that binge ethanol exposure during puberty changes the central expression of stress-related genes in a sex-specific manner, potentially leading to permanent dysregulation of the HPA axis and long-term behavioral consequences. Sequence conservation and direct experimental evidence have implicated sequences within and between the HS cores in function of the LCR.

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New information-based approaches could yield better homeland protection. Sokal of the porque han retirado junifen dosage State University of New York at Stony Brook unveiled a beta-test microcomputer version of their phenetic program package, NT-SYS. Transesophageal echocardiography combined with magnetic resonance imaging for detecting venous anomalies in dextrocardia. This mechanism includes a classical activator-inhibitor system, but is based on the modifications of the membrane structure, rather than a reaction-diffusion system. Determinations of breakpoints require tools such as the understanding of dosing, MIC distributions of organisms without resistance mechanisms, pharmacokinetics, pharmacodynamics, and of clinical outcome in defined clinical situations.

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After the surgery, the patients were trained for synchronous contraction of the trapezius and diaphragm muscles, and electromyography (EMG) was performed to evaluate the synchronization. Early and delayed cardiac mortality after acute myocardial infarction in the pre-thrombolytic era. Furthermore, the development of adipocytes in the hostacycline tetracycline hydrochloride dose skin is independent from that of subcutaneous adipose tissue development. To study the effect of peri-implantitis inflammatory microenvironment on the biological function of jaw bone osteoblasts. Transitions in caregiving: evaluating a person-centered approach to supporting family caregivers in the community.

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Both the models for testing tenox 10 mg pretentious safety and those for testing efficacy suffer from a number of shortcomings. Health professionals need preparation and support to work in collaborative practice teams, a requirement brought about by an aging population and increases in chronic and complex diseases. The aim of this study is to evaluate long-term outcomes regarding readmission for laparoscopy-assisted distal subtotal gastrectomy (LADG) compared to conventional open distal subtotal gastrectomy (CODG) for early gastric cancer (EGC). The virulence of the virus, characterized by the ability to infect Fc receptor-bearing monocytes also influences the development of these severe illnesses.

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HTLV-I viral-associated myelopathy after blood jill magid becoming tarden medicine transfusion in a multiple trauma patient. Epstein-Barr virus-associated typical gastric carcinoma detected by in situ hybridization and polymerase chain reaction. Subluxation of the inferior radio-ulnar joint complicating fracture of the radial head. Drag reducing polymers improve coronary flow reserve through modulation of capillary resistance.