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Klopidogrel (Clopidogrel)

Klopidogrel is a thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group, the methylene hydrogen of which is replaced by a methoxycarbonyl group (the S enantiomer). A P2Y12 receptor antagonist, it is used to inhibit blood clots and prevent heart attacks. It has a role as a platelet aggregation inhibitor, an anticoagulant and a P2Y12 receptor antagonist. It is a thienopyridine, a member of monochlorobenzenes and a methyl ester. It derives from a ticlopidine.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

Similar Products:
Apix, Blistex, Cabre, Tamiram, Clamentin, Buxon, Liroken, Eupantol, Lipofin, Tadalista, Protoner, Radol, Anabact, Zolacos, Sumatran, Astrim, Tamizam, Polypen, Gabapentine, Azadose, Cefobid, Staxyn, Lasilacton, Ropinirole, Priligy, Carbamazepine, Allam, Ritomune, Doxepin, Flotral, Levox, Lamitrin, Citalopram,

Klopidogrel is used alone or together with aspirin to lessen the chance of a heart attack or stroke. It is given to patients who have already had a heart attack, severe chest pain, or a stroke, or to patients with other circulation problems that could cause a stroke or heart attack.

A heart attack or stroke may occur when a blood vessel is blocked by a blood clot. Klopidogrel is a platelet inhibitor. It reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood. Klopidogrel may also increase the chance of serious bleeding in some people.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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We simultaneously performed PSG and actigraphic recordings at both ankles and at the bases of both big toes (Cambridge Actiwatch AW-64) for 40 nights. pulcherrimus, two new riffle beetle species from Borneo, and discussion about elmid plastron structures (Coleoptera: Elmidae). In conclusion, the proposed indicators allow for progress in monitoring the effects of the economic crisis on health and health inequalities in Spain. EtOH-PC ameliorated behavioral deficit induced by cerebral I/R and protected the brain against I/R-induced delayed neuronal death, neuronal and dendritic degeneration, oxidative DNA damage, and glial cell activation. ICH patients were retrospectively identified from our institutional ICH database.

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Mineral concentration gradients in rat femoral diaphyses measured by X-ray microtomography. Effects of valproic acid on gene expression during human embryonic stem cell differentiation into neurons. In addition, individuals with chronic anxiety--those high in Negative Affectivity (NA)--report more symptoms than those low in NA.

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Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation. The maximum effect was observed when using 5 g/l and 10 g/l concentrations of this component. Neural response to reward anticipation in those with depression with and without panic disorder. Left ventricular ejection fraction assessed by echocardiography and radionuclide angiography.

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Castanospermine, an alpha glucosidase inhibitor, prolongs renal allograft survival in the rat. The progressive understanding on hippocampal neurogenesis in aging and mood disorders increases the demand to explore powerful and subtle interventions on hippocampal neurogenesis. We aimed to study the biological mechanisms underlying the observed non-specific and sex-differential effects of MV on mortality. We hope this case presentation will be valuable in increasing the awareness of physicians about this rare cause of tracheal obstruction or difficult intubation. Currently, measurements of clumping index (CI) by handheld instruments is typically time- and labor-intensive.

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In contrast, affective disorder patients exhibited less slow wave generators mainly in frontal and central regions when compared to healthy subjects and schizophrenia patients. Cellular responses were seen to stem from local changes in diffusion dynamics of the adapter protein vinculin and associated impaired mechanotransduction rather than impaired recruitment of proteins involved in focal adhesion formation. Multilamellar hydrodissection increases the predictability and safety of phacoemulsification and planned extracapsular cataract extraction. Small colorectal cancers also do not always mean the early stage.

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The results indicate that small surface areas of test specimens are associated with higher bond strengths and that the effect on tensile and shear values is similar. Nucleotide sequencing was performed on the V3 region and sequences were edited, aligned and translated into amino acids as described in the algorithm. The b mating-type locus of Ustilago maydis contains variable and constant regions. Occurrence and severity of alopecia in patients on combination chemotherapy.

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Subjects with central field defects performed less well than control subjects although no specific impairment could be pinpointed. Biliary excretion of these agents can be used to evaluate the anatomic structure and function of the biliary tree. Cyclin-dependent kinases (Cdks) control cytoskeleton polarization in yeast morphogenesis. Platelet aggregation in PRP is suppressed by hypochlorite by its direct interaction with cells and indirectly due to plasma modification.

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Cochlear implants (CIs) are used for compensating the so-called deep sensorineural deafness. 7-Deaza-2-phenyladenines: structure-activity relationships of potent A1 selective adenosine receptor antagonists. The study was a prospective randomized controlled trial on patients with subacute and chronic subdural hematomas.

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Lipid droplet formation in response to oleic acid in Huh-7 cells is mediated by the fatty acid receptor FFAR4. To determine the prevalence of polyhydramnios in a routine antenatal population, in which first and second trimester ultrasound screening for fetal abnormality had been performed and to examine the outcome in these pregnancies. These results revealed that both in mice and humans, PPARgamma is a thrifty gene mediating Type 2 diabetes.

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Evidence for Extensive Overlap of Sporophytic and Gametophytic Gene Expression in Lycopersicon esculentum. In studies in humans, it was concluded that measurements of maximal voluntary contraction torque and range of motion provide the best methods for quantifying muscle injury.

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This paper describes the techniques for combining arthroscopic treatment of unicompartmental osteoarthritic knees and proximal tibial osteotomy. Nature of states in a random-dimer model: Bandwidth-scaling analysis. We found that there were changes in emphasis in the research field over the four decades. Aneurysm occlusion after subarachnoid haemorrhage (SAH) aims to improve outcome by reducing the rebleeding risk.

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Variations in refractive index and absorbance of 670-nm light with age and cataract formation in human lenses. However, due to the ketamine-induced psychotomimetic effects, new NMDA receptor antagonists (modulators) are continuously being introduced for rapid antidepressant action, especially for use in treatment-resistant patients. Low uKIM-1 levels may help to discriminate postrenal AKI events using a panel of markers in this setting.

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Periodontal conditions of Colombian university students aged 16 to 35. In contrast, growth and proliferation in imaginal tissues are reduced and irregular, resulting in abnormal development of imaginal discs and the CNS of the larvae. Heparin-histamine complex, its physico-chemical and biological properties Our experimental results are validated by detailed three-dimensional computer simulations. These results confirmed our hypothesis that different ACC regions are differentially affected by structural alterations in schizophrenia, a circumstance that might explain in part the discrepant findings of former structural imaging studies of the ACC.

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Transporter associated with antigen presentation (TAP) molecules supply small peptides to the lumen of the endoplasmic reticulum for assembly with MHC class I glycoproteins. Molecular mechanisms of gender disparity in hepatitis B virus-associated hepatocellular carcinoma.

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Angiocardio-aortography with gaseous contrast: its value in the study of renal abnormalities Early PSA decrease is an independent predictive factor of clinical failure and specific survival in patients with localized prostate cancer treated with radiotherapy combined or not with androgen deprivation therapy. Our findings indicate that stimulation of the innate immune system with co-encapsulated immunostimulants in nano-liposomes is a promising strategy to simultaneously improve the levels of protection against bacterial and viral infections in fish.

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Pregnancy was not associated with increased symptoms of depression or anxiety. The aim of this study is to investigate the effects of cardiac integrin-linked kinase (ILK) overexpression tramagesic medicine in a rat model of doxorubicin-induced heart failure and the underlying mechanisms.

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During treatment with tacrolimus and methylprednisolone for relapsed grade 2 acute gut GVHD, fever and disturbance of consciousness occurred on day 210. A commercial kit for DNA preparation from clinical samples, based on nefopam hydrochloride overdose on ibuprofen absorption of nucleic acids to silica gel, was superior to the traditional phenol/chloroform extraction and increased the rapidity, simplicity and sensitivity of the procedure. Cyclic GMP levels in the rat brain and plasma during clinical death and after resuscitation.

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Susceptibility of house flies (Diptera: Muscidae) exposed to commercial insecticides on painted augmentin 1 g max dose of ibuprofen and unpainted plywood panels. Improved analysis of vitamin D metabolites in plasma using liquid chromatography tandem mass spectrometry, and its application to cardiovascular research.

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Lattice dynamics, tolterodine tartrate doses structural stability, and phase transitions in incommensurate and commensurate A2BX4 materials. To study the pathologic characteristics and prognosis in different subtypes of adult medulloblastoma (MB). Thus, it seems that the additional administration of thymopentin in breast and ovarian cancer patients under chemotherapy results in a reduction of immunosuppressive side effects of chemotherapy and a positive effect of the survival time in patients with limited spread of disease.

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To identify the clinical features of optic nerve hypoplasia (ONH) and prevalence within a population of New Zealand children with severe visual impairment. These findings indicate that products of 15-lipoxygenase may act as intracellular messengers in Friend erythroleukemia cells by affecting protein phosphorylation. Astrocyte rosuvastatin vs atorvastatin vs simvastatin dosages growth stimulation by a soluble factor produced by cerebral endothelial cells in vitro.

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No other known causes for haemolytic and uremic syndrome were found. The electrochemically oxidized species had a wide absorption profile spanning from 300 nm to past 800 nm. The frequency of early in utero HIV infection appears to be low, compared with transmission rates in infants born to HIV-1-infected mothers, suggesting that transmission occurs mostly later in pregnancy and/or at delivery. We abduce meaning of names studied exposure to solid fuel and second-hand tobacco smoke among pregnant women in south Asia, Africa and Latin America.