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Symasteride (Finasteride)

Symasteride is used to shrink an enlarged prostate (benign prostatic hyperplasia or BPH) in adult men. It may be used alone or taken in combination with other medications to reduce symptoms of BPH and may also reduce the need for surgery. Symasteride may improve symptoms of BPH and provide benefits such as decreased urge to urinate, better urine flow with less straining, less of a feeling that the bladder is not completely emptied, and decreased nighttime urination. This medication works by decreasing the amount of a natural body hormone (DHT) that causes growth of the prostate. Symasteride is not approved for prevention of prostate cancer. It may slightly increase the risk of developing a very serious form of prostate cancer. Talk to your doctor about the benefits and risks. Women and children should not use this medication.

Other names for this medication:
Finasteride, Androfin, Avertex, Daric, Fenered, Finahair, Finalo, Finalop, Finar, Finara, Finast, Finax, Fincar, Finpecia, Firide, Monast, Prohair, Propecia, Proscalpin, Proscar, Prosteride, Reduprost, Renacidin, Sutrico, Symasteride, Tealep, Tensen,

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Symasteride (Proscar) is used alone or in combination with another medication (doxazosin [Cardura]) to treat benign prostatic hypertrophy (BPH, enlargement of the prostate gland). Symasteride is used to treat symptoms of BPH such as frequent and difficult urination and may reduce the chance of acute urinary retention (sudden inability to urinate). It also may decrease the chance that prostate surgery will be needed. Symasteride (Propecia) is also used to treat male pattern hair loss (gradual thinning of the hair on the scalp, leading to a receding hairline or balding on the top of the head in men.) Symasteride (Propecia) has not been shown to treat thinning hair at the temples and is not used to treat hair loss in women or children. Symasteride is in a class of medications called 5-alpha reductase inhibitors. Symasteride treats BPH by blocking the body's production of a male hormone that causes the prostate to enlarge. Symasteride treats male pattern hair loss by blocking the body's production of a male hormone in the scalp that stops hair growth.

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A highly enriched denitrifying mixed culture transformed o-xylene co-metabolically along with toluene by methyl group oxidation. Consistent with this, increasing (p)ppGpp synthesis by addition of serine hydroxamate or over-expression of relA led to reduced susceptibility to the peptide. A solitary nesidioblastoma was observed in the anterior wall of the duodenum.

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Thus, these results suggest that coexposure to this low-affinity, low-potency ligand for ERalpha specifically antagonizes the E2-induced ERalpha-dependent rapid signals by reducing the effect of the endogenous hormone in promoting cellular proliferation. These data can be used to assist healthcare professionals in the development of educational tools and strategies for promoting cancer screening programs for KAs. The crystal structures of catalytic antibody D2.3 Fab with the two enantiomers, 7D and 7L, which represent transition state analogues for the hydrolysis of the corresponding esters, 6D and 6L, were determined to better understand remarkable reactivity differences: the L-ester displayed significantly tighter binding (K(M)) and increased catalytic activity (k(cat)) with D2.3, even though the chiral center is 7 bonds distant from the reaction center. Sex differences in the dietary modulation of pancreatic cancer in Syrian hamsters treated continuously with N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine. An investigation of the feasibility of applying Raman microscopy for exploring stained glass.

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A significant reduction of met-enkephalin, but not of substance P or neurotensin, was observed in the retina of the eye receiving dim and unpatterned light. H7, a cloned null mutant, and Y8, a control positive for both cat and BAG1, were chosen for further characterization. A comparative approach to the experimental analysis of emotional behavior. Theoretical model for the morphotropic phase boundary in lead zirconate-lead titanate solid solution. The FEPP active control condition can be used as a model in the design of future studies.

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Pediatric pituitary tumors, albeit relatively infrequent, can significantly alter the quality of life of affected children. Chondriosome structure and occurrence of protoplasmic lammellar system of Coprinus disseminatus (Basidiomycetes)

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Typical and atypical antipsychotics and other D2 antagonists behaved similarly, with the exception of clozapine and olanzapine. To report career destinations and views in 1998 of doctors who qualified in the United Kingdom (UK) in 1993. Eccentric electrophoretic motion of a rectangular particle in a rectangular microchannel. The MPM-treated group showed a statistically significant improvement in PD reduction and clinical attachment gain compared to the OM control group. Co-grafts of fetal raphe and septal neurons restored both the cholinergic (muscarinic) and serotonergic receptor functions.

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A spectrophotometric assay of LF activity, based on its reaction with the substrate (Ac-gly-tyr-betaala-arg-arg-arg-arg-arg-arg-arg-arg-val-leu-arg-p-nitroanilide), was used to assess the degree of inhibition of LF by the putative inhibitors. Lysosomes, platelet granules, and neutrophils (polymorphonuclear cells) contain heparanases that degrade heparan sulfate. All of the exposed evidence points to communication between cancer cells and their surroundings, either mediated by cancer cell-derived exosomes or by stromal cell-derived exosomes.

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We show that the degree of competition varies between irrelevant siRNAs and occurs at the point of RISC loading. Androgen receptor functioned as a suppressor in the prostate cancer cell line PC3 in vitro and in vivo. A Harmonic scalpel was used as the only energy source intraoperatively. Positive influence of hyaluronate on cell vitality of human conjunctival cells after alkali injuries. This may explain the prolonged pharmacological effect of rFVIIa.

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We sought to assess the interaction between LVD and LV perfusion pattern in risk-stratification of a large sample size of patients with ESRD. This study shows a high level of self-consciousness and the findings of the studies prove that even the slightest of variations have a greater impact on the above-mentioned dimensions in particular to psychological, functional, and physical aspects. Meanwhile, because of the complexity and multi-factorial nature of obesity, it will still remain as a challenging medical problem.

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No leukopenia, thrombocytopenia or other side effects were observed during the therapy. Across three experiments, we manipulated the type of representation maintained in working memory and the type of representation upon which the participants must exert control to resolve conflict and select a target into the focus of attention. High prevalence of leg disorders in fattening meat turkey farm was observed. In addition, NBNMA activated caspase-8 and caspase-9, initiator caspases of the extrinsic and intrinsic pathways of apoptosis, respectively, which led to activation of executioner caspase-3 along with degradation of poly(ADP-ribose) polymerase. On the basis of the clinical findings and anamnesis, the occurrence of the lesion was attributed to the use of the drug.

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How useful are clinical features in the diagnosis of acute, undifferentiated chest pain? The dynactin subunit dynamitin (also known as p50) is believed to be integral to dynactin structure because free dynamitin displaces the dynein-binding p150(Glued) subunit from the cargo-binding Arp1 filament. Poly(N-isopropylacrylamide) (PIPAAm), exhibiting a lower critical solution temperature (LCST) at 25 degrees C in physiological phosphate buffered saline solution (pH 7.4) and at 32 degrees C in pure water, was grafted onto the surfaces of commercial polystyrene cell culture dishes.

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Pseudorabies virus UL36 tegument protein physically interacts with the UL37 protein. Moreover, ultrasound mediated BBB disruption, in combination with DOX therapy, resulted in a significant increase of survival and in a slower disease progression in the two syngenic GBM mouse models.

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The p24 proteins have been grouped into four subfamilies (alpha, beta, gamma, and delta) and appear to assemble into tetrameric complexes that contain only one representative from each subfamily. Laparoendoscopic single-site adrenalectomy (LESS-A) has been developed as an extension of standard laparoscopic minimally invasive procedures. The enveloped virions are spherical in shape, have a mean diameter of 127 nm, and vary significantly in size. Parameters in the model were estimated with the data collected in actual fecal egg count. These data provide preliminary evidence for unique brain abnormalities in db/db mice in specific areas that are involved in processing of neural signals that can affect the islets of Langerhans, gonadotrophin secretory patterns, and many other visceral functions.(ABSTRACT TRUNCATED AT 250 WORDS)

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Epidemiological studies on risk factors for colorectal cancer (CRC) have mainly focused on diet, and being overweight is now recognized to contribute significantly to CRC risk. The value of regulated upon activation normal T cell expressed and secreted in the pathogenesis of varicose ulcer of lower limbs Soft tissue tumor should be treated by adjuvant chemotherapy with irradiation because of its high frequency of recurrence and metastasis. Neutrophils are endowed with a plethora of toxic molecules that are mobilized in immune responses. There is an apparent consensus on the many aspects of perioperative and postoperative care of pediatric appendicitis among Israeli Pediatric Surgeons (IPS).

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As cells entered the exponential growth phase, there was an 8-fold increase in pyrimidine biosynthesis that was accompanied by a 40-fold increase in MAPK activity and a 4-fold increase in CAD threonine phosphorylation. The process of intrinsic gastric ageing may play a role in inducing abnormalities of gastric epithelial proliferation against injury but, most of the time, pathophysiological modifications observed in older people are the consequences of chronic insults, such as chronic Helicobacter pylori infection, polymedication, especially Proton-pump inhibitors (PPI) and Non-steroidal Anti-inflammatory Drugs (NSAID), and co morbidities.

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Problems with current recommendations for susceptibility testing of Haemophilus influenzae. The influence of general, volatile anesthetics on the dynamic properties of model membranes. The post-operative wrist score ranged from 65 to 100 with an average 81.2 points.

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Continuing professional education: individual responsibility, collective consciousness. Speech, velopharyngeal function, and hearing before and after orthognathic surgery. In contrast to the extrapolated estimates by this method, density functional theory binding energies with B3LYP, B971, and TPSS methods yield the differences from the reference values as large as 3.9 kcalmol with much higher computational cost in most cases, signifying the efficacy of the employed extrapolation scheme for study of large hydrogen-bonded complexes.

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Spontaneous bone loss in RIP-iNOS transgenic mouse: a mouse model for diabetes-mediated osteopenia/osteoporosis. At 10(-5) M CD F-actin and alpha-actinin are preferentially located in different areas of the cell. CT enterography is an important tool in the noninvasive diagnosis and follow-up of pediatric Crohn disease.

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Leukocyte function-associated antigen 1 (LFA-1) is a signaling molecule for cytoskeletal changes in a human T cell line. Electrical and magnetic properties of Nb2O5- delta crystallographic shear structures.

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