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Spiractin (Spironolactone)

Spiractin is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. Spiractin is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spiractin is known as a "water pill" (potassium-sparing diuretic). Spiractin has also been used to treat excessive hair growth (hirsutism) in women with polycystic ovary disease.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Spiractin also is used in combination with other medicines to treat precocious puberty (a condition causing children to enter puberty too soon, resulting in the development of sexual characteristics in girls usually younger than 8 years of age and in boys usually younger than 9 years of age) or myasthenia gravis (MG, a disease in which the nerves do not function properly and patients may experience weakness; numbness; loss of muscle coordination; and problems with vision, speech, and bladder control). Spiractin also may be used to treat certain female patients with abnormal facial hair. Talk to your doctor about the possible risks of using this medication for your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

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Therefore, we studied ROCKII mutant mice to probe this pathway genetically. varSelRF and GeneSrF implement a validated method for gene selection including bootstrap estimates of classification error rate. HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort.

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Severe cardiotoxicity of high-dose 5-fluorouracil in combination with folinic acid, cisplatin and methotrexate in a 14-year-old boy with nasopharyngeal carcinoma (Schmincke tumor). Regulation of stress-activated protein kinase signaling pathways by protein phosphatases. Resistency and retention were considered as the essential factors to achieve the integrity of final restorations. Grids in topographic maps reduce distortions in the recall of learned object locations. Given typical signs, plain radiography of the abdomen should assure diagnosis.

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Molecular screening of virulence genes in extraintestinal pathogenic Escherichia coli isolated from human blood culture in Brazil. Serum nesfatin-1 levels were significantly decreased in women with severe preeclampsia compared with women with mild preeclampsia. The selective f-channel inhibitor, ivabradine, inhibits If currents that play an exclusive role in pacemaking and thereby slows heart rate without altering myocardial inotropy.

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These compounds possessed no antagonist effects on 15-F(2t)-IsoP-induced contractions, No dilator effect was observed in comparison with sodium nitroprusside and acetylcholine on the rat aorta. Mammalian PERIOD proteins act as a scaffold with distinct domains that simultaneously bind CKIepsilon and mCRY1 and mCRY2 (mCRY). The tumour suppressor p53 is activated to induce cell-cycle arrest or apoptosis in the DNA damage response (DDR).

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Therapeutic efficacy of topical unoprostone isopropyl in retinitis pigmentosa. Use of bactericidal ultraviolet radiation for air disinfection in nurseries in the presence of children The neural mechanisms controlling puberty onset remain enigmatic. One pseudopterygium had to be removed surgically because of visual acuity deterioration.

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Micronutrient requirements are well-established for healthy full-term infants. Special attention is paid to the nosology of X-linked mental retardation and familial mental retardation in general.

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The results obtained for enantioseparation of the two drugs using the three CDRs were compiled and compared. Tyr42, Tyr53 and either Tyr94 or Tyr445 were phosphorylated by the Src kinases Fgr, hematopoietic cell kinase (HCK) and Yes. Findings highlight the roles of insomnia and emotion dysregulation in contributing to elevated PTSS among trauma-exposed smokers, and the potential importance of targeting these factors in the context of PTSD treatment. Nevertheless, even in the V2 region, differences were too tenuous for effective identification of L. It is still controversial, however, which mechanism it is that causes the reversible hearing loss.

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The A and H character of the blood group substances secreted by persons belonging to group A2. Although total BNF was higher in secondary than primary forest, overall rates were roughly five times lower than previous estimates for the tropical forest biome.

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The authors investigated scaffold-based therapies designed to augment the success of alveolar repair. Megaloblastic anaemia is a major cause of pancytopenia, and may present acutely in the critically ill. Synergistic effects can be observed when ozonolysis was combined with sonolysis because additional OH was produced. MiRNA targets are transcription factors involved in wheat growth and development, metabolism,and stress responses. The phenotype of recessive cornea plana can rarely include corneal decompensation.

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Using a randomized, double-blind, double-dummy, parallel-group design, 105 patients with reversible obstructive airways disease (77 asthmatic patients) recruited from four referred-care clinics received, in addition to their existing therapy, 4 mg nedocromil sodium four times daily or sustained release theophylline (maximum daily dose 13 mg/kg) for 6 weeks. In the future, owing to the development of the CT technology and image processing technique, virtual cystoscopy may have a part in the detection of bladder cancer. The reasons why the autoreactive clones do not recognize T-cell blasts, as well as their possible implications in regulatory mechanisms involving HLA-class II molecules are discussed. The photoluminescence signals of a graphene/MoS2 heterostructural stacking film are sensitive to environmental charges, which allows the single-base sequence-selective detection of DNA hybridization with sensitivity to the level of aM. A laboratory susceptible and fenitrothion-resistant larval strains were used.

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Several TonB1-TonB(Ec) chimeras were constructed, and assessment of their activities revealed that substitutions at the N or C terminus of TonB1 compromised its activity in P. At the end of the experiments, the serum glucose, cholesterol, triglycerides, low-density lipoproteins, high-density lipoproteins, ghrelin, leptin and nesfatin-1 concentrations were measured. Cytokinesis and the contractile ring in fission yeast: towards a systems-level understanding.

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In the present study, we compared longicin-derived synthetic analogs in order to characterize the antimicrobial motif (P4) by analyzing some structural features using various bioinformatic tools and/or CD spectroscopy. New antiarrhythmic drugs, free of undesired effects, would enhance rhythm control, with the possibility of sinus rhythm restoration and maintenance. Predicting 1-month response of macular edema to intravitreal bevacizumab from 1-hour response.

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Analyses of cultured MEKs were made with the cells attached to the culture dishes. For given values of relative risk and genotype frequency, the discriminative accuracy increases with increasing heritability but declines with increasing prevalence of the disease. The symptom-medication scores were significantly decreased by IT. Circadian and ultradian variations of pituitary and pineal hormones in normal men: evidence for a link between melatonin, gonadotropin, and prolactin secretion.

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Domiphen bromide and didecyl dimethylammonium bromide inhibited HERG channel currents in a dose-dependent manner with IC50 values of 9nM and 5nM, respectively. In vitro, ex vivo, and in vivo experiments in rats were used to assess the adhesive potential of these two proteins expressed in heterologous host Lactobacillus salivarius BGHO1. Genotype-phenotype analysis of TCF4 mutations causing Pitt-Hopkins syndrome shows increased seizure activity with missense mutations.

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A note on a controlled experiment using reserpine, an extract of Alstonia constricta and placebo. Injury characteristics and surgical treatment of lower lumbar vertebral burst fractures Microfluidic technology plays an increasing role in fluidic manipulation in microscale devices used in display areas. No overall significant hepatic disposal or production was found in the patient or control groups but slightly increased production was found in a subset of patients with advanced disease. We sought to describe a subset of children who present with early-onset AF and a slow ventricular response rate who were found to have the short QT syndrome (SQTS).

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But there is a risk of the disease increasing in incidence, in this region. We report a case of tracheopathia osteoplastica of the upper third of the trachea in a young 35-year-old mal, fortuitously discovered while exploring a biliptysis caused by a broken hydatic cyst of the liver. This article describes the range of feelings that nurses may experience in the course of delivering care and relates these feelings to the traumatic event. Correlation and agreement were assessed between these and other parameters (i.e., IL-6, WBC, platelet count, CRP, pH and lactate). These agents are only used for relatively short periods of time ranging from minutes (for irrigants) up to days or several weeks (for medicaments) and therefore their long-term antimicrobial effects rely on whether or not the particular agent has any properties of substantivity.

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Our results therefore indicate that interaction between transcriptional regulators and their target proteins in Mediator are less dependent on the primary sequences in the interaction domains but that these domains fold into similar structures upon interaction. Narrowing of the inner borders of the CS between the right and left side is a statistically significant parameter in acromegaly. We sought to determine the incidence and timing of competitive athletes to return to their prior high-performance level after TOS treatment and surgery.

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Previous studies have suggested the efficacy of foscarnet combined with thymidine analogues as salvage therapy in late-stage HIV-1 infection. Prospective randomized trials should be considered to assess postoperative WAR for OCCA. This case suggests that CPH can undergo malignant transformation, probably as a result of actinic damage.

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The characters of a recurrent lesion may be changed by clonal selection following chemotherapy. Cells were immortalized by expression of the nononcogenic proteins cyclin-dependent kinase 4 (Cdk4) and the catalytic component of human telomerase (hTERT) and maintained for more than 1 year in culture. Electrochemical behavior of these films has been studied using cyclic voltammetry (CV) and amperometric techniques, respectively.

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VARP is a Rab32/38 effector that also binds to the endosomal/lysosomal R-SNARE VAMP7. Although PPARalpha/delta silencing did not affect cholesterol and triglyceride accumulation in PLA-LDL-treated macrophages, PPARdelta activation by PLA-LDL attenuated macrophage inflammatory gene expression induced by interferon gamma and lipopolysaccharide.

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Role of C-reactive protein and procalcitonin in differentiation of tuberculosis from bacterial community acquired pneumonia. Unlike other genome engineering tools such as recombinases and meganucleases, ZFNs do not require preinsertion of target sites into the genome and allow precise manipulation of endogenous genomic scripts in animal and plant cells.

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The effect of Medicaid premiums on enrollment: a regression discontinuity approach. The overall risk of death attributed to cancer in patients with kidney transplants is increased at least tenfold over that in cancer patients in the general population. Interventions that will facilitate health seeking behavior in African-American men are needed in order to impact the health disparity. They then appear to greatly enhance the feasibility of high-dynamic interferometric coronagraphs.

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In contrast, behavioural experiments show the involvement of changes in transduction mechanisms activated by spinal opioid receptors. We identified regulatory light chain (RLC) of smooth muscle/non-muscle myosin-2 as the light chain of Myo19. We measured the concentrations of soluble E-cadherin in several cutaneous diseases, and found higher levels in sera from patients with bullous pemphigoid, pemphigus vulgaris, psoriasis vulgaris and inflammatory skin diseases, compared with controls. Arabidopsis thaliana phytochelatin synthase 2 is constitutively active in vivo and can rescue the growth defect of the PCS1-deficient cad1-3 mutant on Cd-contaminated soil. Metastatic cancer of the small intestine: regarding an ileal epithelioma metastatic from a bronchial epithelioma

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DNA methylation plays a critical role in the regulation of gene expression, genomic DNA stability, cell proliferation, and malignant transformation. It has long been believed that gut microbiota, more specifically, the activity of the microbiome and its metabolic products, directly influence a variety of aspects in metazoan physiology. Application of topical MMC is an efficient treatment for residual conjunctival SCC. Compared with the risk seen in never smokers without depressed mood, depressed mood at the highest level of smoking was associated with relative risks of 4.5 for total cancer, 2.9 for cancer at sites not associated with smoking, and 18.5 for cancer at sites associated with smoking. Results of the measurement of corneal anesthesia as a function of the property of the mechanical stimuli used

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After transseptal puncture, an admixture of 2 cm(3) blood and 1,000 IU of thrombin was injected into the LAA, and imaging of the LAA was repeated. The study population consisted of 146 with CAD (102 with hypertension) and 266 age-matched individuals without CAD (114 with hypertension).

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The application of the VAI in particular populations of patients (women with polycystic ovary syndrome, patients with acromegaly, patients with NAFLD/NASH, patients with HCV hepatitis, patients with type 2 diabetes, and general population) has produced interesting results, which have led to the hypothesis that the VAI could be considered a marker of adipose tissue dysfunction. Liver biopsy was performed, which diagnosed chronic active hepatitis and IFN-alpha was administrated at a dose of 3 Meg unit per day. Direct measurement of the branching ratio for the decay of the eta meson into two photons.

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We report a case that illustrates how mental stress radionuclide imaging has the potential to be used in the assessment of myocardial ischemia non-detected by conventional methods in patients with suspicion of ischemic thoracic pain. lateral mesencephalic tegmentum, torus semicircularis, contralateral large-celled pretectal nucleus, and ipsilateral thalamic nuclei, which have not previously been demonstrated. No significant correlation was observed for HSP90 concentration with the aforementioned indices.

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Ordered metal nanopatterns are crucial requirements for electronics, magnetics, catalysts, photonics, and so on. We therefore sequenced proviral DNA isolated from peripheral blood mononuclear cells from HIV-infected individuals on fully suppressive antiretroviral therapy.

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Multiple linear regression was used for the statistical analyses. Heparin was found to inhibit the DNA binding of antibodies eluted from kidneys of both humans and MRL-lpr/lpr mice with systemic lupus erythematosus. However, genetics also controls the amount (or activity) of the enzymes. It is less frequent to offer training to family medicine residents (10 of 17 regions) and to the different nursing specialties (6 of 17). No cases of clinical mastitis in the dry period were observed in treated cows, whereas in the untreated groups a significant number were observed.

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To identify potential combination partners for JAK2 compounds in MPN cell lines, we performed pooled shRNA screen targeting 5,000 genes in the presence or absence of JAK2 blockade. The purpose of this review is to describe our current knowledge regarding the risk factors, co-occurrence, and recurrence of the conditions of IPD with a specific focus on the preterm gestational window.

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Our results show that (1) lower levels of light available to the retina correspond with an increase in the number of retinal pseudogenes, (2) retinal protein networks generally degrade in a predictable manner, although the extensive loss of cone phototransduction genes in Heterocephalus raises further questions regarding SWS1-cone monochromacy versus functional rod monochromacy in this species, and (3) inactivation dates of retinal genes usually post-date inferred entrances into subterranean habitats. Mortality was tracked for one year using Health Care Finance Administration MEDPRO files. The burden of eclampsia: results from a multicenter study on surveillance of severe maternal morbidity in Brazil.

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In Ara-C-treated mice its plasmatic concentrations decrease while the CFU-S start cycling. Development and validation of liquid chromatography-tandem mass spectrometric method for the quantification of ciprofibrate from human plasma. Isotropic 3D fast FLAIR imaging of the brain in multiple sclerosis patients: initial experience.

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AgNOR numbers in morphologically and clinically verified adrenocortical carcinoma (12 cases) were not different from those in adenoma (17 cases). Telmisartan exerted a longer-lasting BP-lowering effect and greater attenuation of BP variability in SHRcp than valsartan.

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Cardiac action potential wavefront tracking using optical mapping. All animals had a dorsally based random pattern flap created and either bilateral pure axial superficial inferior epigastric (superficial inferior epigastric) flaps or a unilaterally superficial inferior epigastric axial with random component flap.

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The choice of intraocular lens before cataract extraction for cases with high myopia Accelerated water quality improvement during oligotrophication in peri-alpine lakes. Recent studies have shown that epigenetic modifications in mature spermatozoon play an important role in the developing embryo and its alterations in epigenetic patterns may increase the risk for fertilization failure, dysfunction of embryogenesis, preterm birth, low birthweight, congenital anomalies, perinatal mortality, and several other pregnancy-related complications seen at a higher frequency in babies conceived by in vitro fertilization (IVF).

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Characterization of Fetal Tissue-derived Mesenchymal Stem Cells. Study groups: are they effective in preparing students for NCLEX-RN? Thus, we examined E-cadherin methylation in gastric mucosa from H. While infection is usually self-limiting, a minority of patients infected with EV71 develop severe neurological complications. Tissue apoptosis was quantified by histochemistry and Western blotting.

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We studied the use of HB1.F3.CD therapeutic NSCs, a well-characterized clonal cell line derived from human fetal telencephalon, for their potential of secreting prodrug-activating enzyme. Snoring did not accelerate subclinical change in carotid atherosclerosis during a four-year follow-up, although baseline difference in IMT between snorers and non-snorers was significant in women, independent of witnessed sleep apnea. Immunoblotting with an antibody recognizing Cx45 revealed a band at approximately 46 kDa in homogenates of mouse turbinates and olfactory bulb. The molecular mechanisms underlying the maintenance of the GSC phenotype are not fully defined. ranvir singh parents name Atropine as an antisialogogue, compared with l-hyoscyamine (bellafoline), scopolamine butylbromide (buscopan) and oxyphenonium (antrenyl).

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Two further putative subunits, Csn4 and Csn5, were identified from the S. For the induction of atherosclerosis, the rabbits were placed on a high cholesterol diet (HCD) for 11 weeks. Eighty of these children have reached adult height, with a bone atropina nombre generico de norvasc age of at least 16 years in the boys and at least 14 years in the girls, and pubertal stage 4 or 5.

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We find that in 2007, employment-based plans covered 80 percent of all charges paid by the plan and the member, while individual plans covered verschil tussin oxazepam alprazolam dosage 64 percent. We decided to use this new cystoscope to resect a bladder tumor and coagulate the bleeding because the patient could tolerate only local anesthesia due to severe heart disease complications. The average win/loss increased for several forms of gambling, providing a modest indication that gamblers were betting more, albeit less frequently.

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An IKK inhibitor (IKK 16) or vehicle was administrated 1 symbal 20 mg hour before the induction of VILI. At the cost of slightly reducing angular resolution, the Laplace-Beltrami regularization reduces ODF estimation errors and improves fiber detection while reducing angular error in the ODF maxima detected. Radiofrequency-induced heating near fixed orthodontic appliances in high field MRI systems at 3.0 Tesla. Transformation and trends in preventive and social medicine education at the undergraduate level in a Brazilian medical school. A meta-analysis of the literature shows that in adult male songbirds, brain mass, telencephalon volume and n.

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It is possible that pantoprazole dura 40 mg erfahrungen antisense-TGF-beta1 may be used for gene therapy in glomerular diseases. Nasal surgery and upper airway radiofrequency ablation in patients with obstructive sleep apnea hypopnea syndrome It has been proposed that the shape of the lipid A component determines the bioactivity of LPS, with lipid A that adopts a conical conformation being more active than lipid A that adopts a cylindrical shape. CSF-1R is also sensitive to Imatinib and this sensitivity is altered by mutation D802V. In this paper, we demonstrate use of single-channel independent component analysis to extract respiratory patterns from the tracheal sounds before, during and after HFCC therapy, and use basis features in the tracheal sound to detect the change in respiratory patterns.

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Our structure revealed an unexpected zinc ion in one interface, which stabilizes mCRY1-mPER2 interactions in vivo. In 2K1C rats, urinary excretion of EETs was significantly lower and that of 20-HETE was higher than that in sham-operated animals only on day 27 after clipping. However, the success and safety of primary colonoscopic screening has not been prospectively zonalon ointment for eczema evaluated in a multicenter trial.

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Endovascular therapy for acute and chronic lower-extremity deep venous disease seeks to improve patency and flow to ameliorate severe symptoms, prevent the postthrombotic syndrome, and treat existing chronic venous disease. Spin polarization and magnetic dichroism in photoemission from core and valence states glipizide dose in rats in localized magnetic systems.

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Pd based and Au based couples have been found to be more corrosion-resistant than base alloy couples. irritans at the highest doses tested (10(-6) g), as did the positive control 1-octen-3-ol. There is potential for selecting the anti-inflammatory actions of the EETs by preventing their metabolism by the soluble epoxide hydrolase. We conclude that the histopathological reaction of the mammalian lesioned spinal lafutidine vs pantoprazole cord, when adequately directed by a scaffolding structure can be beneficial for the expression of the intrinsic regenerative capacity of the spinal cord tissue.

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Incorporation of mesoporous silica particles in gelatine gels: effect of particle type and surface modification on physical properties. Frequency of removal of different teeth in persons aged 35-44 years Epirubicin cardiotoxicity: a study perindopril vs other ace inhibitors of 135 patients with advanced breast cancer. Influence of RpoS, cAMP-receptor protein, and ppGpp on expression of the opgGH operon and osmoregulated periplasmic glucan content of Salmonella enterica serovar Typhimurium. Antibody against chromatin assembly factor-1 is a novel autoantibody specifically recognized in systemic lupus erythematosus.